Metabolism of Acid Mucopolysaccharides

Metabolism of Acid Mucopolysaccharides in the Shwartzman Phenomenon

The effect of the Shwartzman phenomenon on the metabolism of the acid mucopolysaccharides (MPS), hyaluronic acid and chondroitin sulfate, from rabbits with localized lesions was studied. Quantitative changes of MPS were observed by two techniques-the in vivo incorporation of glucose C(14) into the MPS and the in vitro dilution of C(14)-labeled MPS. The results indicate an increased concentratio...

Metabolism of Acid Mucopolysaccharides in the Shwartzman Phenomenon* by Gerald

The two-stage inflammatory state observed by Sanarelli (1) and by Shwartzman (2) is considered an interesting, although not entirely understood, reaction of tissue. The reaction localized to skin, referred to as the Shwartzman phenomenon, represents a special type of inflammatory change, one requiring "preparation" of tissue by intracutaneous injection, usually of an endotoxin from Gram-negativ...

Mucopolysaccharides and sodium metabolism.

This paper deals with the possible relationship between a native, negatively charged polyelectrolyte, chondroitin sulfate, and sodium metabolism. The physical chemical property of decreased activity of the cations Na, K and Ca in chondroitin sulfate is described. The data of experiments indicating an alteration in the inueoprotein metabolism of the cartilage of the rabbit's ear in response to t...

Mucopolysaccharides and Sodium Metabolism

This paper deals with the possible relationship between a native, negatively charged polyelectrolyte, chondroitin sulfate, and sodium metabolism. The physical chemical property of decreased activity of the cations Na, K and Ca in chondroitin sulfate is described. The data of experiments indicating an alteration in the inueoprotein metabolism of the cartilage of the rabbit's ear in response to t...

Metabolism of the mucopolysaccharides of connective tissue.